PROBIOTICS AND DYSBACTERIOSIS: CAUSES, CONSEQUENCES, AND TREATMENT APPROACHES
DOI:
https://doi.org/10.37547/Keywords:
probiotics, dysbacteriosis, microbiota, intestinal health, fecal microbiota transplantation (FMT), prebiotics, gut-brain axis, immune modulationAbstract
Dysbacteriosis, or intestinal dysbiosis, refers to a qualitative and quantitative imbalance in the gut microbiota, often resulting from antibiotic use, chronic stress, or metabolic disorders. This imbalance may lead to gastrointestinal infections, inflammatory bowel diseases, and even systemic effects on the immune, nervous, and endocrine systems. Probiotics—live microorganisms beneficial to the host—play a critical role in restoring microbial balance and preventing dysbiosis-related disorders. Recent therapeutic advancements such as fecal microbiota transplantation (FMT), synbiotics, and dietary modulation have shown promising results in clinical trials. This review summarizes current knowledge about the pathophysiology, clinical manifestations, and modern treatment strategies for dysbacteriosis, emphasizing the scientific evidence supporting probiotic interventions.
Downloads
References
1. Explanatory Dictionary of Human Physiology (2011) – Definition of dysbacteriosis.
2. Cleveland Clinic Health Library – Causes and consequences of intestinal dysbiosis.
3. NIH Office of Dietary Supplements – Mechanisms and definitions of probiotics.
4. Gut Microbiota for Health resources – Infographics on microbiota diversity and diet.
5. Karimi et al., Frontiers in Immunology (2024) – Review on fecal microbiota transplantation and modern therapy.
6. Asghari et al., Scientific Reports (2023) – Clinical effects of probiotics on inflammatory markers.
7. Hempel et al., JAMA Network (2012) – Meta-analysis on probiotics for antibiotic-associated diarrhea.
8. Cleveland Clinic Lifestyle Section – Dietary and preventive recommendations for microbiota health.
Downloads
Published
Issue
Section
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Articles published in this journal are licensed under the Creative Commons Attribution 4.0 International License (CC-BY 4.0). Under this license:
- Share: Copy and redistribute the material in any medium or format
- Adapt: Remix, transform, and build upon the material for any purpose, including commercially
Attribution required: You must give appropriate credit, provide a link to the license, and indicate if changes were made.
License URL: https://creativecommons.org/licenses/by/4.0/
Authors retain copyright of their work while granting the journal first publication rights.
