PROBIOTICS AND DYSBACTERIOSIS: CAUSES, CONSEQUENCES, AND TREATMENT APPROACHES

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Dilmurodov Doston Dilshod o‘g‘li
Maxmedov Suxrobjon Vahobjon o‘g‘li
Yuldoshov Jasurbek Davron o‘g‘li
Shavkatov Otabek To‘lqinbek o‘g‘li
Hoshimov Muhammad Asror o‘g‘li
Boltayev Farxod Ro‘zimovich

Abstract

Dysbacteriosis, or intestinal dysbiosis, refers to a qualitative and quantitative imbalance in the gut microbiota, often resulting from antibiotic use, chronic stress, or metabolic disorders. This imbalance may lead to gastrointestinal infections, inflammatory bowel diseases, and even systemic effects on the immune, nervous, and endocrine systems. Probiotics—live microorganisms beneficial to the host—play a critical role in restoring microbial balance and preventing dysbiosis-related disorders. Recent therapeutic advancements such as fecal microbiota transplantation (FMT), synbiotics, and dietary modulation have shown promising results in clinical trials. This review summarizes current knowledge about the pathophysiology, clinical manifestations, and modern treatment strategies for dysbacteriosis, emphasizing the scientific evidence supporting probiotic interventions.

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How to Cite

PROBIOTICS AND DYSBACTERIOSIS: CAUSES, CONSEQUENCES, AND TREATMENT APPROACHES. (2025). International Bulletin of Medical Sciences and Clinical Research, 5(11), 95-100. https://doi.org/10.37547/

References

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2. Cleveland Clinic Health Library – Causes and consequences of intestinal dysbiosis.

3. NIH Office of Dietary Supplements – Mechanisms and definitions of probiotics.

4. Gut Microbiota for Health resources – Infographics on microbiota diversity and diet.

5. Karimi et al., Frontiers in Immunology (2024) – Review on fecal microbiota transplantation and modern therapy.

6. Asghari et al., Scientific Reports (2023) – Clinical effects of probiotics on inflammatory markers.

7. Hempel et al., JAMA Network (2012) – Meta-analysis on probiotics for antibiotic-associated diarrhea.

8. Cleveland Clinic Lifestyle Section – Dietary and preventive recommendations for microbiota health.

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