According to some researchers, middle age is not just a period when women experience hot flashes and other symptoms of menopause. This is a time when their risk of cardiovascular disease increases as we see significant changes in multiple clinical measures of their physical health.

Wu Q, Zhang L, Zheng J, et al. Forensic pathology study of 1,656 sudden cardiac deaths in Southern China. Medicine 2016; 95:e2707.

The NAMS 2017 Hormone Therapy Position Statement Advisory Panel: The 2017 hormone therapy position statement of The North American Menopause Society. Menopause . 2017;24(7):728–53.10.1097/ GME .0000000000000921 [ PubMed ].

Burke AP, Farb A, Malcom GT, Liang Y, Smialek J, Virmani R. Risk factors influencing the mechanism of acute thrombosis and sudden coronary death in women. Circulation 2018.

Abu-Assi E, López-López A, González-Salvado V, et al . The risk of cardiovascular events after an acute coronary event remains high, especially during the first year, despite revascularization. Rev Esp Cardiol (Engl Ed) 2016; 69:11-8 .

Association Of Age At Onset Of Menopause And Time Sinceonset Of Menopause With Cardiovascular Outcomes, Intermediate Vascular Traits, And All-Cause Mortalitya Systematic Review And Meta-Analysis. Taulant Muka, Clare Oliver-Williams .

Setor Kunutsor, Joop SE Laven, Bart CJM Fauser, Rajiv Chowdhury, Maryam Kavousi, Oscar H. Franco. Jama Cardiology | Original Investigation. October 2016 Volume 1, Number 7.Page768-774 .

Associação Brasileira de Climatério (SOBRAC). Consenso Brasileiro de Terapêutica Hormonal da Menopausa. [Internet] São Paulo: SOBRAC; 2014 [accessed on 02 Feb 2017]. Available at: http://sobrac.org.br/publicacoes/artigos#Sobrac .

Bashu Dev Pardhe, Sumitra Ghimire, Jyotsna Shakya, Sabala Pathak, Shreena Shakya, Anjeela Bhetwal, Puspa Raj Khanal, and Narayan Prasad Parajuli. Elevated Cardiovascular Risks among Postmenopausal women: A Community Based Case Control Study from Nepal. 2 May 2017. Biochemistry Research International journal . R 1-4.

Burke AP, Farb A, Malcom GT, Liang Y, Smialek J, Virmani R. Risk factors influencing the mechanism of acute thrombosis and sudden coronary death in women. Circulation 2018; Witte C., Meyer Zur Heide Genannt Meyer-Arend JU, Andrié R. et al. Heart Rate Variability and Arrhythmic Burden in Pulmonary Hypertension // Advances in Experimental Medicine and Biology. – 2016. – V.934. – P. 9-22.

B. T. Akkiev, R. D. Kurbanov. The relationship between heart rate variability and ventricular extrasystole during left ventricular systolic dysfunction in patients with myocardial infarction: scientific publication // Cardiology of Uzbekistan. - Tashkent , 2018. - N 3 . - C. 34-38. - Bibliography: 15 titles.

Associação Brasileira de Climatério (SOBRAC). Consenso Brasileiro de Terapêutica Hormonal da Menopausa. [Internet] São Paulo: SOBRAC; 2014 [accessed on 02 Feb 2017]. Available at: http://sobrac.org.br/publicacoes/artigos#Sobrac .

S. V. Nedogoda, I. N. Barykina, V. Yu. Khripaeva, A. S. Salasyuk, V. O. Smirnova. Metabolic disorders in postmenopausal women and methods for their correction // Medicinal Bulletin. - No. 3 (55) 2014 Volume 8. - P. 10-18.

Tolstov, S.N. Cardiometabolic risk factors in menopausal women, possibilities for correcting identified disorders / S.N. Tolstov, I.A. Salov, A.P. Rebrov // Diary of the Kazan school. – 2017.- No. 2 (16).- P. 25–32.

Mychka, V.B. Modern treatment options for patients with metabolic syndrome - focus on the endothelium / V. B. Mychka // Russian Journal of Cardiology. - 2014. - No. 3. – pp. 107-130.

Decree of the President of the Republic of Uzbekistan No. UP-4947 dated February 7, 2017 “On the Action Strategy for the further development of the Republic of Uzbekistan.”

Noroozi M., Rastegari Z., Paknahad Z. // Iran. J. Nurs. Midwifery. Res. – 2010. – Vol. 15. – No. 1. – R. 27–31.

Burt VL, Whelton P, Roccella EJ, et al. // Hypertension. – 1995. – Vol. 25. – R. 305–313.

Stimpel M. , Zanchetti A. , Walter de Gruyter Hypertension after Menopause. – Berlin–New York, 1997.

Smetnik V.P. Tumilovich L.G. Non-operative gynecology: a guide for doctors. – M., Medical Information Agency. – 1997. – P. 238–312.

Medic V.A., Tokmachev V.S. Manual of Health and Healthcare Statistics : Publishing house: Medicine 2006.- 528 p .