IMMUNOHISTOCHEMICAL ANALYSIS OF AGE-RELATED FACTORS IN POST-TRAUMATIC FORMS OF RHINOSINUS POLYPS
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Abstract
This study investigates the age-related immunohistochemical characteristics of post-traumatic rhinosinus polyps. Morphological and immunohistochemical analyses of polyp tissues were performed, including the assessment of T- and B-lymphocytes, macrophages, and cytokine expression, with comparisons across different age groups. The results demonstrate that age significantly influences the immunological profile of polyp tissue, with notable differences in inflammatory cell activity and cytokine expression observed in younger patients. This research provides insights into the pathogenesis of post-traumatic rhinosinus polyps and the mechanisms of age-dependent immune responses, offering valuable data for the development of individualized clinical management strategies.
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