ANALYSIS OF ANTIMICROBIAL AND ANTIFUNGAL ACTIVITY OF SYNTHETIC STRUCTURAL COMPOUNDS
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This analysis examines data from authoritative sources, as well as some data without changes and citations. A review of 1,3,4-oxadiazole derivatives shows a high potential for their antimicrobial activity. The new structures have a very wide range of activity, from bacteria and fungi to protozoa and viruses. The possible mechanisms of action of some of the new compounds, which are based on the inhibition of various enzymes, for example, DNA gyrase, enoyl reductase and lanosterol-14α-demethylase, are described. Many of the new derivatives exceed the activity of already known antimicrobials.
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