DEPENDENCE OF THE DEVELOPMENT OF CONGENITAL INSUFFICIENCY IN HUMANS ON ONTOPHYLLOGENESIS
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Abstract
This article provides a scientific and theoretical analysis of the relationship between the origin and development of congenital malformations in humans and the processes of ontophylogenesis. Based on the laws of ontogenesis and phylogenesis, the influence of morphological and functional changes occurring at the stages of embryonic development on the formation of congenital defects is highlighted. Also, the causes of congenital malformations are revealed based on the integration of critical periods of embryonic development, genetic and epigenetic factors, and environmental influences into the ontogenetic process. The article analyzes the phylogenetic roots of some congenital defects from the point of view of evolutionary development and substantiates their theoretical and practical significance for medical and biological sciences.
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References
1.Gilbert S.F. Developmental Biology. 11th ed. Sunderland: Sinauer Associates, 2016.
2.Sadler T.W. Langman’s Medical Embryology. 14th ed. Philadelphia: Wolters Kluwer, 2019.
3.Carlson B.M. Human Embryology and Developmental Biology. 6th ed. Elsevier, 2021.
4.Moore K.L., Persaud T.V.N., Torchia M.G. The Developing Human: Clinically Oriented Embryology. 11th ed. Elsevier, 2020.
5.Larsen W.J. Human Embryology. 5th ed. Philadelphia: Churchill Livingstone, 2017.
6.Wolpert L., Tickle C., Arias A.M. Principles of Development. 6th ed. Oxford: Oxford University Press, 2019.
7.Hall B.K. Evolutionary Developmental Biology. 3rd ed. Springer, 2015.
8.Carroll S.B. Endless Forms Most Beautiful: The New Science of Evo-Devo. New York: W.W. Norton, 2005.
9.O‘zbekiston Respublikasi Oliy ta’lim muassasalari uchun “Odam anatomiyasi va embriologiyasi” darsligi. Toshkent, 2020.
10.Xolmatov A., Rahmonov B. Embriologiya asoslari. Toshkent: Fan, 2019.
11.Karimov U. Rivojlanish biologiyasi va ontogenez masalalari. Biologiya va tibbiyot muammolari. 2021;3:45–52.
12.Abduqodirov S. Tug‘ma nuqsonlarning embriologik asoslari. Toshkent: Universitet, 2022.