RISK FACTORS FOR THE DEVELOPMENT OF SEVERE BRONCHIAL ASTHMA
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Abstract
The aim of our study was to evaluate the clinical manifestations and risk factors for the development of bronchial asthma (BA) in children. We examined 80 children aged 1 to 16 years with BA who were hospitalized in the pulmonology department of the Andijan Regional Medical and Clinical Center. In moderate to severe asthma, a longer duration of shortness of breath, oral wheezing, wet cough, and wet rales in the lungs was observed. In the presence of severe bronchospasm, symptoms of intoxication, night attacks, fatigue, respiratory failure, and deterioration of spirographic parameters were more pronounced, which manifested themselves in long-term clinical signs of the disease. Among the main risk factors for the development of bronchial asthma, one can highlight hereditary burden, the degree of increase in the level of immunoglobulin E in the blood, the characteristics of the mother’s nutrition during pregnancy and lactation, early transfer of the child to mixed and artificial feeding, unfavorable course of the peri- and intranatal periods and comorbid background.
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