VITAMIN THERAPY IN LIVER CIRRHOSIS WITH SPECIAL EMPHASIS ON NEUROVITAN: PATHOPHYSIOLOGY, CLINICAL APPLICATION, AND REGIONAL PRACTICE (UZBEKISTAN EXPERIENCE)

Authors

  • Ibragim R. Askarov Andijan State University Professor of the Department of Chemistry, Doctor of Chemistry, Honored Inventor of Uzbekistan, Chairman of the TABOBAT Academy of Uzbekistan
  • Khabibullo N. Kodirov Andijan State Medical Institute Assistant of the Department of Propaedeutics of Internal Medicine

DOI:

https://doi.org/10.37547/

Keywords:

liver cirrhosis, vitamin therapy, Neurovitan, B-complex vitamins, hepatic encephalopathy, Uzbekistan, Andijan, alcoholic liver disease

Abstract

Liver cirrhosis is a chronic progressive liver disease characterized by diffuse fibrosis, regenerative nodules, and irreversible destruction of normal hepatic architecture. It remains a major global and regional public health problem, including in Uzbekistan, where viral hepatitis B and C and alcohol-related liver disease are the leading causes. Nutritional deficiencies, particularly of B-group vitamins, are highly prevalent in cirrhotic patients and significantly contribute to neurological, metabolic, hematological, and immunological dysfunction.

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References

1.European Association for the Study of the Liver. EASL Clinical Practice Guidelines for decompensated cirrhosis. J Hepatol. 2018.

2.AASLD Practice Guidance on Cirrhosis Management. Hepatology. 2023–2025.

3.World Gastroenterology Organisation. Global Guidelines: Cirrhosis. 2023.

4.O'Shea RS, Dasarathy S, McCullough AJ. Alcoholic liver disease. Hepatology. 2010.

5.Butterworth RF. Thiamine deficiency and brain disorders. Nutr Res Rev. 2013.

6.Plauth M et al. ESPEN guideline on clinical nutrition in liver disease. Clin Nutr. 2019.

7.Bemeur C, Butterworth RF. Nutrition in cirrhosis and hepatic encephalopathy. Clin Liver Dis. 2016.

8.Mendenhall CL et al. Protein-calorie malnutrition in cirrhosis. Am J Clin Nutr. 1995.

9.Morgan MY. The treatment of hepatic encephalopathy. Metab Brain Dis. 2016.

10.Askarov IR. Clinical and biochemical aspects of hepatology in Uzbekistan. Andijan. 2022.

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Published

2026-06-10

How to Cite

VITAMIN THERAPY IN LIVER CIRRHOSIS WITH SPECIAL EMPHASIS ON NEUROVITAN: PATHOPHYSIOLOGY, CLINICAL APPLICATION, AND REGIONAL PRACTICE (UZBEKISTAN EXPERIENCE). (2026). International Bulletin of Medical Sciences and Clinical Research, 6(6), 19-25. https://doi.org/10.37547/

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