OPTIMIZATION OF PHARMACEUTICAL TECHNOLOGY FOR COMBINED ANTIDIABETIC PREPARATIONS IN UZBEKISTAN
DOI:
https://doi.org/10.37547/Keywords:
combined antidiabetic preparations, pharmaceutical optimization, medicinal plants, granulation technology, bioavailability, Uzbekistan, diabetes mellitusAbstract
The rapid increase in diabetes mellitus cases in Uzbekistan has created a need for innovative pharmaceutical solutions capable of improving therapeutic effectiveness and reducing treatment-related complications. Combined antidiabetic preparations containing herbal components and synthetic active substances have become an important direction in pharmaceutical research due to their multifunctional pharmacological activity. The present article analyzes pharmaceutical technological approaches aimed at optimizing the production of combined antidiabetic medicines in Uzbekistan. The study focuses on innovative extraction methods, granulation technologies, bioavailability enhancement, and stabilization of active compounds in combined dosage forms. Particular attention is devoted to local medicinal plants with hypoglycemic potential and their incorporation into modern pharmaceutical formulations. The findings demonstrate that technological optimization significantly improves product stability, dissolution properties, and pharmacological efficiency.
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