ALZHEIMER'S DISEASE AND THE MECHANISMS OF MEMORY LOSS

Ibrohimjon Kozimov; Orifxo’ja Nazirjonov

doi:10.37547/

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Published: 2025-10-14

DOI: https://doi.org/10.37547/

Keywords:

Alzheimer’s disease, memory impairment, amyloid-beta plaques, tau pathology, synaptic loss, neuroinflammation, cognitive dysfunction

Kozimov Ibrohimjon Elmurod o’g’li

Kokand University, Andijan Branch Field of Study: Pediatrics Group: 25-02 Student:

Nazirjonov Orifxo’ja Xusanxo’ja o’g’li

Clinical and Pathological Anatomy Department:

Abstract

Alzheimer’s disease AD is a chronic neurodegenerative condition characterized by progressive cognitive decline, particularly affecting memory. This disorder involves complex molecular and cellular changes in the brain, including the accumulation of amyloid-beta plaques, abnormal tau protein formations, loss of synaptic connections, oxidative stress, and inflammatory responses. These pathological events disrupt normal neuronal communication and contribute to the gradual deterioration of memory and other cognitive functions. Understanding the mechanisms behind memory impairment in AD is essential for developing new therapeutic approaches and improving patient care. This review summarizes current knowledge on the biological processes that lead to memory loss in Alzheimer’s disease and highlights potential targets for intervention.

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Issue

Vol. 5 No. 10 (2025): International Bulletin of Medical Sciences and Clinical Research

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Articles

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

ALZHEIMER’S DISEASE AND THE MECHANISMS OF MEMORY LOSS. (2025). International Bulletin of Medical Sciences and Clinical Research, 5(10), 41-43. https://doi.org/10.37547/

References

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