ALZHEIMER'S DISEASE AND THE MECHANISMS OF MEMORY LOSS
DOI:
https://doi.org/10.37547/Keywords:
Alzheimer’s disease, memory impairment, amyloid-beta plaques, tau pathology, synaptic loss, neuroinflammation, cognitive dysfunctionAbstract
Alzheimer’s disease AD is a chronic neurodegenerative condition characterized by progressive cognitive decline, particularly affecting memory. This disorder involves complex molecular and cellular changes in the brain, including the accumulation of amyloid-beta plaques, abnormal tau protein formations, loss of synaptic connections, oxidative stress, and inflammatory responses. These pathological events disrupt normal neuronal communication and contribute to the gradual deterioration of memory and other cognitive functions. Understanding the mechanisms behind memory impairment in AD is essential for developing new therapeutic approaches and improving patient care. This review summarizes current knowledge on the biological processes that lead to memory loss in Alzheimer’s disease and highlights potential targets for intervention.
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