HORMONAL IMBALANCE AND CAUSES OF FEMALE INFERTILITY: A CLINICAL AND PATHOPHYSIOLOGICAL REVIEW

Authors

  • Shokirova Ruxsoraxon Iskandar qizi Student, Faculty of Medicine Qo‘qon University, Andijan Branch

DOI:

https://doi.org/10.37547/

Keywords:

female infertility, hormonal imbalance, ovulatory disorders, PCOS, thyroid dysfunction, reproductive endocrinology

Abstract

Female infertility is a multifactorial condition frequently associated with hormonal imbalance affecting the hypothalamic–pituitary–ovarian axis. Disorders in endocrine regulation can disrupt ovulation, menstrual regularity, and endometrial receptivity. This article reviews the major hormonal causes of female infertility, including polycystic ovary syndrome, thyroid dysfunction, hyperprolactinemia, luteal phase defects, and metabolic influences. Mechanisms, diagnostic approaches, and current management strategies are discussed. Understanding endocrine-related infertility is essential for early diagnosis and targeted therapy.

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References

1.World Health Organization. Infertility definitions and reproductive health indicators.

2.Practice Committee of the American Society for Reproductive Medicine. Evaluation of infertility.

3.Fauser B.C.J.M. et al. Polycystic Ovary Syndrome — pathophysiology and treatment.

4.Balen A. Ovulatory disorders and infertility management.

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6.Melmed S. Hyperprolactinemia and reproductive dysfunction.

7.Legro R.S. PCOS and insulin resistance.

8.Rosenfield R.L. Ovarian and adrenal androgen excess.

9.Fritz & Speroff. Clinical Gynecologic Endocrinology and Infertility.

10.Teede H.J. Evidence-based PCOS guidelines.

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Published

2026-01-31

How to Cite

HORMONAL IMBALANCE AND CAUSES OF FEMALE INFERTILITY: A CLINICAL AND PATHOPHYSIOLOGICAL REVIEW. (2026). International Bulletin of Medical Sciences and Clinical Research, 6(1), 122-125. https://doi.org/10.37547/

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