EARLY DIAGNOSIS OF RETINOBLASTOMA IN CHILDREN
DOI:
https://doi.org/10.37547/Keywords:
Retinoblastoma, early diagnosis, pediatric oncology, ocular tumor, leukocoria, ophthalmology, genetic testing, childhood cancer, vision preservation, tumor screening.Abstract
Retinoblastoma is the most common intraocular malignancy in children, originating from the immature retinal cells of the eye. Early diagnosis plays a critical role in improving survival rates, preserving vision, and preventing metastasis. This article discusses the etiopathogenesis, genetic background, clinical features, and modern diagnostic approaches for early detection of retinoblastoma in children. Emphasis is placed on the importance of timely screening, the role of molecular and imaging technologies, and the collaboration between pediatricians, ophthalmologists, and oncologists in achieving favorable outcomes. Early recognition of symptoms such as leukocoria and strabismus, combined with advanced imaging modalities and genetic counseling, enables clinicians to identify retinoblastoma at an early stage, leading to effective management and improved quality of life for affected children.
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References
1. Shields, J.A., Shields, C.L. Intraocular Tumors: An Atlas and Textbook. 4th ed. Philadelphia: Lippincott Williams & Wilkins, 2016.
2. Kanski, J.J., Bowling, B. Clinical Ophthalmology: A Systematic Approach. 9th ed. Edinburgh: Elsevier, 2020.
3. Avery, G.B., MacDonald, M.G., Mullett, M.D. Neonatology: Pathophysiology and Management of the Newborn. 8th ed. Philadelphia: Lippincott Williams & Wilkins, 2021.
4. Rudolph, C.D., Rudolph, A.M. Rudolph’s Pediatrics. 23rd ed. New York: McGraw-Hill Education, 2018.
5. Kumar, V., Abbas, A.K., Aster, J.C. Robbins and Cotran Pathologic Basis of Disease. 10th ed. Philadelphia: Elsevier, 2021.
6. Khurana, A.K. Comprehensive Ophthalmology. 8th ed. New Delhi: Jaypee Brothers Medical Publishers, 2022.
7. Ryan, S.J. Retina, Volume 1–5. 6th ed. Amsterdam: Elsevier, 2022.
8. Yanoff, M., Duker, J.S. Ophthalmology. 5th ed. Philadelphia: Elsevier, 2019.
9. Phelps, D.L., Reynolds, J.D. Neonatal and Pediatric Ophthalmology. 3rd ed. New York: Springer, 2017.
10. Parsons, J.H., Asbury, T. Parsons’ Diseases of the Eye. 23rd ed. New Delhi: Butterworth-Heinemann, 2020.
