Chronic endometritis is an understudied pathology associated with adverse reproductive outcomes such as implantation disorders and recurrent miscarriages. We provide summary information from the current literature, summarizing information obtained by searching computer databases. It is more common in infertile patients. With effective antibiotic therapy, SE improves pregnancy, live birth rates in patients with recurrent miscarriages during pregnancy and increases the miscarriage rate in patients with recurrent implantation failure. In addition to traditional histology, immunohistochemistry is recommended to improve diagnostic accuracy. In addition, hysteroscopy can be considered as an effective diagnostic standard, given its high correlation with histologic findings. Bacterial interaction with the endometrial microenvironment contributes to alterations in leukocyte population, cytokine and growth factor production, which enhances its negative impact on endometrial susceptibility. Nevertheless, it is important to define the standardization of histopathological diagnostic criteria and immunohistochemistry methods.

endometritis, hysteroscopy, immunochemistry, reproductive outcomes

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