Currently, in Khorezm, every second woman is aged 40 years and older, life expectancy women on average is 72 years. The increase in life expectancy has led to the fact that the modern woman spends almost 1/3 of his life in the period of menopause. With changes in the age structure of the population, diseases of women of transitional age occupy a special place. Wherein one of the main problems of this period is menstrual dysfunction, clinically manifested acyclic uterine bleeding, oligomenorrhea, menorrhagia, metrorrhagia, or polymenorrhea.

Antonova I. B. Individualization of diagnostic and therapeutic tactics in endometrial hyperplastic processes in the perimenopausal period: author. dis.cand.

honey. Sciences. - M., 1999.

Vikhlyaeva E. M. Guidelines for diagnosis and treatment uterine leiomyomas / Vikhlyaeva E. M. - M .: MEDpress-inform, 2004. - 400 p.

Gumenyuk E. G. Clinical and pathogenetic approach to therapy Dysfunctional uterine bleeding in perimenopause: Abstract of the thesis. dis. … cand. honey. Sciences. - M., 1999.

Zaidieva Ya. Z. The function of the endometrium in perimenopause. Hormone replacement therapy / Zaidieva Ya. Z. // midwife and gin. - 2000. - No. 3. - S. 8-11.

Kulakov V. I. Gynecological endocrinology: newaspects of old problems / 6.Kulakov V. I. // Midwives. and gin. —2003. - No. 1. - S. 6–9.

Kustarov V. N. Dysfunctional uterine bleeding / Kustarov V. N., Chernichenko I. I. - St. Petersburg: Publishing House of St. Petersburg MAPO, 2005. - 164 p.

Lopukhov D. A. Clinical and diagnostic characteristics combined benign pathology of the uterus in perimenopause: Ph.D. dis. cand. honey. Sciences. - M., 1992.

Proliferative activity and apoptosis in hyperplastic endometrium / Sukhikh G. T., Chernukha G. E., Smetnik V. P.[and others] // midwife. and gin. - 2005. - No. 5.-S. 25–29.

Repina M. A. Menopausal metabolic syndromeand obesity / Repina M. A. // Zh. midwife. and wives. disease. —2003. - T. LII, Issue. 3. — P. 75–78.