DYNAMICS OF CLINICAL AND LABORATORY PARAMETERS IN THE POST-STROKE PERIOD OF OUTPATIENT MONITORING
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Abstract
Ischemic stroke remains one of the leading causes of disability and mortality. In a study of 287 patients, it was shown that the recovery of functional abilities depends not only on clinical factors but also on social conditions. In the early period, pronounced neurological deficits and multiple cognitive impairments were observed. Changes in hemostasis, elevated levels of inflammatory markers (sICAM-1, MPO, sE-selectin), and increased platelet adhesion were identified, which increased the risk of recurrence. The use of a combination of acetylsalicylic acid and clopidogrel reduced the risk of recurrent stroke, while the addition of TMS and choline alphoscerate increased rehabilitation effectiveness by 1.5 times. Secondary prevention includes correction of risk factors and lifestyle modification.
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