The rapid advancement of digital technologies is transforming healthcare into a patient-centered, efficient, and accessible system. This article examines the key prospects and opportunities of healthcare digitalization, with a focus on the integration of telemedicine, artificial intelligence, wearable technology, and big data analytics. Additionally, the article explores the real-world implementation of these technologies, highlights success stories, and addresses persistent challenges, including privacy concerns and the digital divide.

This article is devoted to the study of changes in digestive function in people with pulmonary fibrosis. In addition, in this work, residual changes in the morphology of the esophagus caused by stressful situations were studied, that is, morphological changes in the esophageal wall at different stages of pulmonary fibrosis.

COVID-19 infection has become a major concern for the medical community. Various studies have shown that COVID-19 disruptions in the immune system, increased metabolic demand, and procoagulant activity caused by coronavirus can lead to adverse outcomes in the population with cardiovascular diseases [1, 2, 3,4].

Aesthetic dentistry, or cosmetic dentistry, is a specialized field that focuses on improving the appearance of teeth, gums, and smiles. While many people associate this branch of dentistry with procedures like teeth whitening, veneers, or dental implants, one of the most critical elements in aesthetic dentistry is color. Color not only influences the final appearance of a patient's smile but also plays a central role in achieving natural-looking results that blend seamlessly with the patient’s overall facial features. This article explores the importance of color in aesthetic dentistry, focusing on how it affects treatments, the selection of materials, and the overall patient satisfaction.

Cushing's syndrome is a pathological condition of the body characterized by the effect of excessive amounts of the hormone cortisol produced by the adrenal glands. The main cause of the disease is a violation of the regulatory mechanisms responsible for the functioning of the hypothalamic-pituitary-adrenal system.,

Premature infants present unique nutritional challenges due to their physiological immaturity and increased metabolic demands.  Optimal nutrition is crucial for their growth, development, and long-term health. This article provides a comprehensive overview of feeding premature infants, encompassing evidence-based practices, current recommendations, and recent advances in the field. We explore enteral and parenteral feeding methods, address common feeding challenges, and emphasize the importance of individualized care plans and ongoing monitoring to optimize outcomes for this vulnerable population.

Antiphospholipid syndrome (synonyms: antiphospholipid antibody syndrome, lupus antibody syndrome, Hughes syndrome) is a systemic autoimmune disease associated with hypercoagulation and caused by the synthesis of antiphospholipid antibodies (aPL): anticardiolipin antibodies (aCL, lupus anticoagulant (LA), antibodies to b2-glycoprotein I (anti-b2-GP Despite the fact that APS is most often considered in the context of gynecological pathologies, as one of the causes of abortion, defining it as exclusively gynecological is incorrect: the disease occurs in any population group and has a blurred clinical picture. The vigilance of a doctor of any specialization regarding this condition is especially important, since timely prescribed therapy improves the quality of life of patients and long-term prognosis, preventing the development of life-threatening complications.

Ischemic heart disease or cardiac ischemia is a chronic or acute disorder of the blood supply to the myocardium (the muscle layer of the heart). This condition is caused by an insufficient supply of oxygen to the heart. This occurs when arterial blood is supplied to the heart muscle in limited quantities due to damage to the coronary arteries. The acute form of ischemic heart disease is myocardial infarction, the chronic form is angina pectoris.

Changes in heart rate are a major regulator of normal cardiac output, and thus a key component of adaptations in the cardiovascular system. The direct regulation of heart rate at the cellular level has evolved with a complex system of processes that regulate the currents across the cardiac membranes. These set spontaneous cyclic activation and lengths of the action potential which determine the lengths of systole and diastole. This cyclic nature of cardiac output creates important limitations on the circulation because it sets the time available for filling and the time available for ejection. These limits affect the maximum possible outputs from the heart and can lead to pathological processes. Heart rate is regulated by intrinsic processes in the membranes of the pacemaker of the heart (sinoatrial node), the conducting system of the heart, and neural and humoral regulating factors. Heart rate normally increases in proportion to what is called the relative workload but also can be altered by many factors not directly related to metabolic needs. The interplay of all these factors need to be considered by critical care physicians managing patients at the bedside.

According to various authors, one of the most common diseases of the mammary glands is fibrocystic disease or, as it is often called, mastopathy [1]. Fibrocystic disease is not only one of the most common, but also one of the most heterogeneous in clinical, radiological, and histological manifestations of diseases. Such mosaicism is due to the multifactorial nature of the disease. In its formation, a leading role is played by various hormonal disorders, stress, and reproductive dysfunction; with age, the frequency of mastopathy increases.

A pituitary adenoma is a tumor of the endocrine system, the manifestations of which are hyper- or hyposecretion of hormones of the anterior pituitary gland, as well as clinical symptoms caused by the impact of the neoplasm on the anatomical structures surrounding the sellar region. Among intracranial tumors, pituitary adenomas occupy third place, accounting for 7.3 to 18% of all verified brain tumors and affecting mainly people of working age, which accounts for about 75% of all cases of the disease

Prostate cancer is a major public health problem throughout the developed world. For patients with clinically localised prostate cancer, the diagnosis is typically established by histopathological examination of prostate needle biopsy samples. Major and minor criteria are used to establish the diagnosis, based on the microscopic appearance of slides stained using haematoxylin and eosin.The incidence of prostate cancer shows strong age, race, and geographical dependence. Less than 2% of cases are diagnosed under the age of 41, although this may represent an underestimate as screening for disease in young men is rare. Prostate cancer is relatively uncommon in Asian populations and prevalent in Scandinavian countries, and the highest incidence (and mortality) rates known are in African Americans. Causes of the disease are essentially unknown, although hormonal factors are involved, and diet may exert an indirect influence; some genes, potentially involved in hereditary prostate cancer (HPC) have been identified. A suspect of prostate cancer may derive from elevated serum prostate-specific antigen (PSA) values and suspicious digital rectal examination (DRE) finding.

Chronic duodenitis is a disease characterised by inflammatory, dystrophic and regenerative changes in the duodenal wall, predominantly affecting the mucosa. These changes are accompanied by structural reorganization of the glandular apparatus, the development of metaplasia and atrophy, and a prolonged course.

Diabetes insipidus (DI) is an endocrine condition involving the posterior pituitary peptide hormone, antidiuretic hormone (ADH). ADH exerts its effects on the distal convoluted tubule and collecting duct of the nephron by upregulating aquaporin-2 channels (AQP2) on the cellular apical membrane surface. DI is marked by expelling excessive quantities of highly dilute urine, extreme thirst, and craving for cold water. The two main classifications of DI are central diabetes insipidus (CDI), characterized by a deficiency of the posterior pituitary gland to release ADH, and nephrogenic diabetes insipidus (NDI), characterized by the terminal distal convoluted tubule and collecting duct resistance to ADH.

Periodontitis of baby teeth is an inflammatory disease of periodontal tissues surrounding the roots of temporary teeth. This is a common problem in pediatric dentistry, often occurring as a complication of untreated deep caries or pulpitis. The structural features of baby teeth and the immunological features of the child's body contribute to the faster development of inflammatory processes.

Tooth caries is a widespread chronic disease that affects people of all age groups. This article explores the etiology, progression, complications, and management strategies of caries, emphasizing prevention and treatment methods. A detailed review of existing literature, methodologies, and findings is provided, along with practical recommendations for clinical and public health practices.

The follicle and egg are key elements of the female reproductive system. They are closely related to each other and are involved in the processes of maturation, ovulation and reproduction. Their structure is carefully adapted to perform these functions.

Lack of timely contact with the health care system leading to out-of-hospital death or delayed presentation remains a major obstacle to more effective management of patients with AMI.

Conditional diseases of the oral mucosa can be divided into 3 groups: 1.traumatist, mechanic, physicist, chemist, stomatitis, leukoplakies (dysplastic, hyperplasty), nicotine stomatitis. 2.medical disease often,but not all experts agree on the disease. This guru was one of the first to turn to Krishna. specialists (oncologists, dermatologists, allergists, an appeal to hematologists sketches.

Rheumatoid arthritis (RA) is a chronic systemic autoimmune inflammatory disease of the connective tissue, mainly characterized by erosive-destructive polyarthritis of the peripheral joints. RA is a chronic autoimmune disease characterized by joint inflammation, damage, and loss of function. This article reviews the etiology, pathogenesis, clinical features, diagnosis, and treatment of RA. It also discusses the impact of the disease on quality of life and future research directions as well as modern treatment approaches

Dental anomalies are a common pathology and are detected in 30-50% of the adult population. The most common type is the crowded position of the teeth (33.7%). Depending on the severity and combination with the absence of individual teeth, they can lead to aesthetic and functional disorders [1, 2]. Such patients are characterized by a lack of space in the dental arch and various variants of incorrect tooth placement. At the same time, there is a decrease in the value of the longitudinal length of the dental arch relative to the amount of the sum of the mesiodistal size of the crowns of the teeth that form it [3]. One of the most common anomalies is crowding of incisors. Multiple incorrect tooth positions are often noted.

Caries is a pathological process in which the destruction of hard tooth tissues (enamel, dentin) occurs under the influence of acids formed as a result of the vital activity of bacteria in plaque.

Hematopoietic organs (hematopoietic organs) are organs that are involved in the formation, development and destruction of blood cells. They can be divided into central and peripheral hematopoietic organs. Let's consider their structure and functions.

The article discusses the activities of general prevention of offenses carried out by the offense prevention services of internal affairs bodies, and offers proposals and recommendations for the more effective organization of this activity.

Diabetes mellitus (DM) refers to a group of common metabolic disorders that share the phenotype of hyperglycemia. Several distinct types of DM are caused by a complex interaction of genetics and environmental factors. Depending on the etiology of the DM, factors contributing to hyperglycemia include reduced insulin secretion, decreased glucose utilization, and increased glucose production. The metabolic dysregulation associated with DM causes secondary pathophysiologic changes in multiple organ systems that impose a tremendous burden on the individual with diabetes and on the health care system. It also predisposes to cardiovascular diseases. With an increasing incidence worldwide, DM will be a leading cause of morbidity and mortality for the foreseeable future.

The unique properties of chitin and chitosan attract the attention of many specialists in various fields of science. The role of biopolymers in our lives is recognized by everyone. This article presents the results of obtaining chitosan biopolymer from a new promising source - narrow-clawed crayfish. Information about the narrow-clawed crayfish and its distribution in Uzbekistan is also provided.

In the face of rapid healthcare changes and the integration of cutting-edge imaging modalities, it is essential to update approaches to radiological practice. This review presents an analysis of these transformations and outlines future directions for the field of radiology.

In this article, we will determine the concept of overweight and obesity levels among women, and determine which levels of obesity are common among women, and which stages of obesity levels meet in women. Determining the frequency of additional comorbid diseases as a result of obesity. The causes of obesity in women are studied and analyzed statistically. The order in which diseases occur in women and men and their percentages, statistics of changes in obesity depending on age and gender are considered.

Justification the need to use an interdisciplinary approach to the treatment of patients with edentulous based on an analysis of literature data on the relationship between the clinical manifestations of orofacial pain, occlusion and temporomandibular joint pathology in patients with partially missing teeth. The classification, etiology and manifestations of orofacial pain syndrome are described. It is indicated that in most cases, when planning complex orthodontic rehabilitation, it is necessary to ensure the creation of certain mutually protective occlusal schemes by correcting the position of the jaws, in particular by ensuring acceptable occlusal vertical dimensions. 

Periodontal diseases, like the well-known caries, are widespread among the population the entire globe. According to the World Health Organization, about 95% of the adult population and 80% of children have signs of periodontal disease. Clinical forms of periodontal diseases in children differ greatly from similar conditions in adults. All pathological processes develop in a child in growing, developing and reconstructing tissues, which are still morphologically and functionally immature and may inadequately respond to similar stimuli and causal factors that cause periodontal diseases in adults. Of great importance in the pathogenesis of the development of the disease is the possibility of a disproportion in the growth and maturation of immature structures, which can arise both within the system (tooth, periodontium, alveolar bone,etc.), and in the structures and systems that provide and adapt the entire body to external conditions from birth to old age.This causes the occurrence of juvenile gingivitis, periodontitis and periodontoma, which arise as a result of temporary transient functional hypertension, carbohydrate metabolism disorders (juvenile diabetes, diencephalic syndrome, etc.).

This article highlights the specific aspects of ensuring the economic rights of citizens in Uzbekistan, examines the opinions of scholars in this regard, and presents proposals and recommendations developed by the author.