ZAMONAVIY FARMAKOTERAPIYADA NEYROPROTEKTIV DORI VOSITALARINING METABOLIK MEXANIZMLARI VA PEDIATRIYA AMALIYOTIDA QO'LLASH SAMARADORLIGI
DOI:
https://doi.org/10.37547/Keywords:
farmakologiya, neyroproteksiya, nootroplar, gipoksiya, metabolizm, pediatriya, asetilxolin, GAMK, antioksidantlar.Abstract
Ushbu tadqiqot ishida gipoksik-ishemik va metabolik zararlanishlarda qo'llaniladigan nootrop hamda neyroprotektiv dori vositalarining molekulyar va metabolik ta'sir mexanizmlari qiyosiy tahlil qilingan. Bosh miya to'qimasida oksidativ stressni kamaytirish, ATF sintezini rag'batlantirish va neyrotranzmitterlar muvozanatini tiklashda ushbu vositalarning tutgan o'rni baholangan. Pediatriya amaliyotida neyroprotektorlarni kompleks terapiya tarkibida qo'llashning kliniko-farmakologik samaradorligi va xavfsizlik profili o'rganilgan.
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