MODERN APPROACHES TO THE DIAGNOSIS OF CUTANEOUS PSEUDOLYMPHOMAS
DOI:
https://doi.org/10.37547/Keywords:
cutaneous pseudolymphoma, cutaneous lymphoma, immunohistochemistry, molecular diagnostics, lymphoproliferative disorders.Abstract
Cutaneous pseudolymphomas represent a heterogeneous group of reactive lymphoproliferative disorders characterized by benign lymphoid hyperplasia of the skin resulting from prolonged antigenic stimulation. Despite their benign nature, pseudolymphomas demonstrate significant clinical and histopathological similarities with primary cutaneous lymphomas, which complicates the diagnostic process. In recent years, interest in this problem has increased due to the growing incidence of lymphoproliferative skin diseases and the need for accurate differential diagnosis between reactive and neoplastic processes. This article reviews modern diagnostic approaches to cutaneous pseudolymphomas, including clinical, histopathological, immunohistochemical, and molecular-genetic methods.
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