FARMATSEVTIK TAHLILDA SPEKTROFOTOMETRIK USULLARNING QO‘LLANILISHI
DOI:
https://doi.org/10.37547/Keywords:
farmatsevtik kimyo, spektrofotometriya, ultrabinafsha nurlanish, ko‘rinadigan nur, optik zichlik, Buger–Lambert–Ber qonuni, dori vositalari, sifat nazorati, miqdoriy tahlil, instrumental tahlil.Abstract
Ushbu maqolada farmatsevtik tahlilda spektrofotometrik usullarning nazariy va amaliy ahamiyati, dori vositalarining sifatini baholashdagi o‘rni hamda zamonaviy farmatsevtik laboratoriyalarda qo‘llanilish imkoniyatlari yoritilgan. Spektrofotometriya moddalarning elektromagnit nurlanishni yutish xususiyatlariga asoslangan instrumental tahlil usuli bo‘lib, dori moddalarini identifikatsiyalash, ularning miqdorini aniqlash, tozalik darajasini baholash va tayyor dori shakllarining sifat ko‘rsatkichlarini nazorat qilishda keng qo‘llaniladi. Maqolada ultrabinafsha va ko‘rinadigan sohalardagi spektrofotometrik tahlilning asosiy prinsiplari, Buger–Lambert–Ber qonuni, optik zichlik va yorug‘lik o‘tkazuvchanligi tushunchalari, kalibrlash usullari hamda tahlil natijalarining aniqligiga ta’sir qiluvchi omillar haqida ma’lumot berilgan. Shuningdek, spektrofotometriyaning tabletkalar, kapsulalar, eritmalar, inyeksiya preparatlari va boshqa farmatsevtik shakllarni tahlil qilishdagi amaliy imkoniyatlari ko‘rib chiqilgan. Ushbu usulning tezkorligi, yuqori sezgirligi, nisbatan kam miqdordagi namuna talab qilishi va avtomatlashtirish imkoniyati uning farmatsevtik sifat nazoratidagi ahamiyatini yanada oshiradi.
Downloads
References
1. O‘zbekiston Respublikasi Sog‘liqni saqlash vazirligi. Dori vositalari va farmatsevtika faoliyatiga oid me’yoriy-huquqiy hujjatlar.
2. O‘zbekiston Respublikasining dori vositalari va farmatsevtika faoliyatiga oid qonun hujjatlari.
3. Farmatsevtik kimyo fanidan oliy ta’lim muassasalari uchun o‘quv qo‘llanmalar.
4. Farmatsevtik tahlil va dori vositalari sifat nazoratiga oid o‘quv-uslubiy adabiyotlar.
5. Davlat farmakopeyasi. Dori vositalarining sifatini nazorat qilish bo‘yicha umumiy talablar.
6. European Pharmacopoeia. General methods of analysis.
7. United States Pharmacopeia–National Formulary. General Chapters.
8. British Pharmacopoeia. Analytical methods and quality requirements.
9. World Health Organization. Quality assurance of pharmaceuticals.
10. World Health Organization. Good practices for pharmaceutical quality control laboratories.
11. International Council for Harmonisation. Analytical Procedure Development and Validation.
12. International Pharmaceutical Federation. Pharmaceutical quality and analytical control.
Downloads
Published
Issue
Section
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Articles published in this journal are licensed under the Creative Commons Attribution 4.0 International License (CC-BY 4.0). Under this license:
- Share: Copy and redistribute the material in any medium or format
- Adapt: Remix, transform, and build upon the material for any purpose, including commercially
Attribution required: You must give appropriate credit, provide a link to the license, and indicate if changes were made.
License URL: https://creativecommons.org/licenses/by/4.0/
Authors retain copyright of their work while granting the journal first publication rights.
