BOSH MIYA GIPOFIZ BEZINING ANATOMIYASI VA GIPERPROLAKTINEMIYAGA OLIB KELUVCHI KASALLIKLAR
DOI:
https://doi.org/10.37547/Keywords:
Gipofiz bez, adenohipofiz, neurohipofiz, prolaktin, laktotrop hujayralar, giperprolaktinemia, prolaktinoma, endokrin tizim, gipofiz adenoması, reproduktiv tizim disfunktsiyasi, hormonal disbalans, diagnostika va davolash, dofamin nazorati, klinik simptomlar, mikroskopik va makroskopik anatomiyasi.Abstract
Gipofiz bez (hypophysis) — inson organizmida endokrin tizimning markaziy regulatorlaridan biri bo‘lib, turli gormonlar ishlab chiqarish orqali boshqa endokrin organlar va tizimlar faoliyatini boshqaradi. Gipofizning anatomik tuzilishi — adenohipofiz (old lob) va neurohipofiz (orqa lob) — uning funktsional imkoniyatlarini belgilaydi. Adenohipofizda laktotroplar tomonidan prolaktin gormoni ishlab chiqariladi, bu gormon ayollarda sut bezlari faoliyatini va reproduktiv tizimni tartibga soladi, erkaklarda esa spermatogenez va reproduktiv funktsiyaga ta’sir ko‘rsatadi.
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References
1.Guyton AC, Hall JE. Textbook of Medical Physiology. 14th Edition. Philadelphia: Elsevier; 2020.
2.Williams Textbook of Endocrinology. 14th Edition. Melmed S, Polonsky KS, Larsen PR, Kronenberg HM (eds). Philadelphia: Elsevier; 2020.
3.Ten S, New M, Maclaren N. Clinical review 130: Hyperprolactinemia and prolactinomas. J Clin Endocrinol Metab. 2019.
4.Melmed S. Pituitary-Tumor Endocrinopathies. N Engl J Med. 2021.
5.Larsen PR, Kronenberg HM, Melmed S, Polonsky KS. Williams Textbook of Endocrinology.
6.Jameson JL, De Groot LJ (eds). Harrison’s Principles of Internal Medicine. 21st Edition. New York: McGraw-Hill; 2023.
7.UpToDate. Clinical manifestations and diagnosis of hyperprolactinemia; Management of prolactinomas.
8.Endocrine Society Clinical Practice Guidelines. Prolactinoma: Diagnosis and Management.
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